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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '160639a0f1f3e025f424e2c3e0281f9af724bf6076244023633bce08e54aa5c4' 
  AND token = 'GMpTbX63zsjx/+jEi+s352dXJC8bfCh3uD+hhrZPbjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}