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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '59da2e07a17f4b4ddbddfe0eba64b09fa4efe2dff4a30c9e432ca183a383a2b9' 
  AND token = 'g4JRUpf2yRbgA+/8DXsFBTqCjBiA6KDclEPRx2v7SQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}