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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c8c71e0119dd88ae6e30c3eca2b4a621315c6c2b1ff71c134f3e6273c77f28c3' 
  AND token = '+qiDmQKP5+EgI0KEz/wIZi486aSW5DpHy6pYvg2izKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}