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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9c8f96e7a4355d7d77baf668ff81435a0a351603511fcf60c9078d2a476e59bb' 
  AND token = 'rMhS884KfI18EGyCOUjH8tcw1BE8ZVZ8Urv26T9vzcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}