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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '307a32408e13b691a836c74ec5475f526ae969d50513da559327aa618e92a49f' 
  AND token = 'oDYDyO3Nv+2lU7I2nAH4VDSO4QSLOAk43GfPFo3gjGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}