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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2d405a9dc9f8d8c28714e729c104f5a9a509d7c798da4b4c50dcecb63f4e7821' 
  AND token = 'ky9jW9WErGf8wzfz6FKwLw33vpfh5c2XrRHUGNysd08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}