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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4ac2a8e0aaa6d7f54014771c07867e90180544f0493df7c22dadd54acf470669' 
  AND token = 'higLVLKzYERYoSDi7Jdk5RpcakQg95ecVNLmfIndz5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}