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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '886f7aff67ff57e7c5dc58aaf9effb03308777c9052ca1068e71e4c4971d81c2' 
  AND token = 'cmG8UGlxZpSpGrxmcsHtULdy/zzlEXxZP3IdNlQ5zbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}