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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '424d254a269f59f24e7ec587673387f0b1f828c66a0ea2e763c95f9b4ad94796' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}