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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e2226fd2f165b863aa343c4e8dbb928aa0abbe368f0b5db5d4440d88308b0d86' 
  AND token = 'N7qNE4asmWR/NQnuYFjQA8bTEoKgWPx4tuk0SFHlatI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}