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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c6dbade584f00bf2ec72d7f8c45b37c79873cc15cb797ae3752b0f8c00012d8b' 
  AND token = 'lTaQmnps/U+mtaY6Mp3XuoTVj3Rk52OM168/yfP0IqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}