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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '57f58ac47708ed69e00a5676516c7c54aa39f5689a22e1b11c02bc9202a10653' 
  AND token = '8f6iXI323/MqERJJBtZ005ADoaeZKCgm+z188tT/kXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}