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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '617160d26ef04c503cfec3bdbaf657eb18934a53279f4cf4a518f9f3dca295ab' 
  AND token = '7RzKcyzGrHuL09dpSmxnMBfeXl/seWaE0T1ahndf8rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}