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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ae01544a7405fe4a4b67cfd634bd06ca0445d91a3df02290f6efb3450bd4722c' 
  AND token = '1Cn24MpyGDNAyzt/Pcwsp0Y3+rhvBONQM0vwAYdVR0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}