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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '74351d33b9c0729c79a660388ad2619500c14b0eb1f8373666cc7bf62df177b1' 
  AND token = '6LmcTSyTt64UFkWluaAvolVbamM6z8DyFw/r2YMEA/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}