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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '60c6b78fb17c5b591455fd920192ac177dddf57b60ade37ce1f376892fa27682' 
  AND token = 'AM6jWI4/mSKkn06HvnZnSBTA1yXrUQTmeyfm16nUpQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}