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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ab29a60c0c503a82aab6f99cbb4771858a344e90930e7c6d96a292942ff2871c' 
  AND token = 'Ek+jEY2F0otsbpYA4Pma215r6OLJmlcJO6lMw3QPPkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}