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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e381c8b8b5e629182c182cf092800810b3f0d83cf5a8310a16ea69b45c7b8859' 
  AND token = 'j6bJ2DJnsHIkthaCsg3hdeNpGSwGwmLo2nRBBBm3x1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}