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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'dc643370f018426909f6200e22262117902a2733453cd3051da5534f473ecf28' 
  AND token = 'fTJBYk/UR8Hf0HIPMtkI5mCuafS0gULsbcYQD3RDo2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}