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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '43682e75f1e46f07b60d924754da08bb0a8233b98b8e051fa71c25d3ee27f1de' 
  AND token = '22M6YQr21Q5k/kVMdSfsNjbkOiOVQl/iEIMfF8I7yDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}