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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2ebd52de00cfa622dce6c88b68e94cd2f108b1aeb24269110c5e5302e6c585b0' 
  AND token = '02p80UcrFKRGhfOlArBm3Hjw4HA1HcHJ59bppqKdFiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}