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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'edc7d55780ab9f01e58c005e7a0791efc47e0294dcc9b9cf48e9f1304d6310fb' 
  AND token = 'mI25t5Y9yCZlNuTMwQpMwe43IRSY9JLe3Uh5fWpbTAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}