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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd9ee969d1ce25b5010555686bb976f61af09dbad4ae3c324b30b62160c296e37' 
  AND token = 'TRzG1eJsFNMO0l1LScGvqRnFtiNRI8qmsVDBuVFEVKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}