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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'beaae20c2e25e3381eb851f8cd92a79bb489f20a81c7947482d5dc8c08401355' 
  AND token = 'qzDT33JUPTu5lhcUGur+yGm2LSCsRbtQHW0KN4bhN9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}