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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '521e1398c1d5be8607076dac1ddd1e4b5dbd1a0743c1d340cd4698237d7e1593' 
  AND token = '0Jo4PDCBkuugeEg+cCubfNQdEuLyMLyBeQMOBXukuEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}