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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '28559980eb5c41303e328603c8d57aa35e788b067eda5106fb0e0b9090284fed' 
  AND token = 'CpQ9ms/rWdbvosiXVnmwo8+7S01jCCqL4zLnZUDtVRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}