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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e75b5e104f5bfe2eea42e7e233bb2bab934f19176951a2f9f3d42e758900de80' 
  AND token = 'lBRpUw3lbe+6t5DfT5SuRpJIMTIseMnzY9VMuuG3S98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}