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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '186d6b9c80a26685ce994947359e9616d619d878bfa86b03e377287875c8120e' 
  AND token = 'ydkNw6Sm5GPXK75AT+M66/j9IBSCRvuMjMNwHNm4vMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}