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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6d1bfcf680bf8a55875e22453cc2022b6f3b2cef3b3b85874a5d549f05488890' 
  AND token = 'keuLxn5CojmxQdr21bBD9fdGs5n434CI3qPV4D5zIhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}