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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '25e1718a0ff2496725365320ea5195872f94101f7e5a513a6520a5ded4316f66' 
  AND token = 'qw/cn54ee1UNUpH59IglD6KU30TZ49wUoXh8EVfcZ4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}