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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0e1f0228c3312598d6dd1530b507901a3d19d87c584d2022599c3ac0d28f79a2' 
  AND token = 'iuW/A1cJobJsXLnanpzmiCevehfnl7ygX8ZqQd387Hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}