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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '46259ef3a3676fe1cbddec8fd7ea1b5f7bdd22349def99ebab612dbe797eb2ce' 
  AND token = 'CpVCQU03F+yh09h9wPmpQGLTXqXiFdHIgYWnndlVd+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}