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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '66b4f5d146b09c7e95d870a4fe826053bef328a7c1146f28e181c77a431ad458' 
  AND token = 'WG36oZkGJ1ehYprNes6X8p2fsb0YlBqekAB9CKBoYDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}