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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6b6b28797d77e5831bdb1ce27c497dc73673584806ac9f828ead28576a431849' 
  AND token = 'oakk5a4Z4zn/dValBcWfJD1bCJpkaJfTG/IT9yIPn2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}