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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1d6ce78fc4729274744366de13553da1eaabd488df3815fc1b64a33838ccfed1' 
  AND token = 'g3g7/MzcpGwmM37EUn7xzmCvy2D4wdfuFZfxDV/IQUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}