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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '351c393eea96ffb5917273e038ac2e88fa789752bcf414a4bc51db4bfa0a8510' 
  AND token = 'c+rdgDZ67265huZggNrCp1ECx0odbbyWxkFnGQiSpFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}