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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e6497769a254d351c2495e3694afae23a40c8fcdf8e2396c420cfec370e77690' 
  AND token = '4qUk3GsqlaEL6JgTULBCo7K59nUSyGEa1F5/1OIwZE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}