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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '53c0d0c8a4c502da4ba71f337c1dba2cd1545b539778daa24d557b139901b2b1' 
  AND token = 'fj3S2G4QqIu0B1FyNcGN3aEhVD6SYnakRQyCf7xTkrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}