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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2e56c6a3e775c4330e8e251c14386f5e12defa15fb5fde17632f0f652634d7fe' 
  AND token = 'yrUWe7uZfS8OEq/zHizcqlmFaHTij+6mY0/ItiGI8m0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}