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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5165cd6348fa2621b053059bc387f216e880af018edebbd3830c81a00fd9ec6a' 
  AND token = 'F/DMGjh5OR6P6sbi1DGcS3/KPaYHA8usTtvKFuvprzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}