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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9181f902bf48ddff9379e9b887e08780bd71a586a3d7337f4d94c799d42c36b6' 
  AND token = 'XVCJJPVyCmIRTt1bk1bPFd8fwdZ9lJWOkVRioP5sohI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}