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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2bc6f9cfb4d94a4ee4b11d0311f0685091893cf453762f70c7635ff27e52c481' 
  AND token = 'RcVXpxV0f3kyk2m5+XTpzIKvTKxmcSv2Nz6ZdgKM4vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}