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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '844c4dbacef2e49920386feb7b70590c81bfa147d9c5b4935a90101ee7fae548' 
  AND token = 'TUEvl4TiKFkfDLW1vE1szAfqZqe9Voiji/gCbDDp3eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}