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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3df033933397f95d394ec5292bb0cac2df37c23102bc891ac0a46a87b3febb77' 
  AND token = '7RIVi+TX/sEDw2Dj68BThTXNomnqCnlumMMHjjeRwsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}