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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b34b24c23d8f61111f64b59207b753049e160c5cb0ed09aa0c0a110b44f971dc' 
  AND token = 'ltxVObzp0sgai/kZyGaTQiRKg5E37gopQGXcaC8TrDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}