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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0fe2f12c4f1d7beca7b88d3be8a5fe4da4a527c04f2872a43a05c1c07eb68171' 
  AND token = 'E1k0dnb22wESWOa25p9Bbke8ljML741mv+kewfiNcq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}