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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e9144c707c249c20c280a191f92cc67ea758e5faacbf41198057b490e304c2e8' 
  AND token = 'Mzp1qxpjbB9pvZFrjmLwmRxpcS76kw5G8ZhO8zdz3e4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}