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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8ffb1b295e6a08ab43b0fe51d6feca158d49f0e521b2451c8c24e1667bc0d78a' 
  AND token = '+DVi6u8477Pcnxks3oQ7jpCtuRyI5ExE70ZKkY44fsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}