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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4c6b18d69bcd626e43104ce793731b4fa664f050c41772e01dd79366bd05d01f' 
  AND token = 'PQLz2M4HmueheSyzdF7mDv4BZm71Ba/tFEHsxuwLAyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}