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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1c3eea8d34adaf6e0995a2de67661bd695ec7344e84e080bba9b2666e85331da' 
  AND token = 'x5n9iE00Buz3aU2W5ecxFtJxvMcPgbz0JbnGDP+eq8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}